Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Naltrexone is a prescription medication used to reduce the desire to drink by blocking endorphins released when alcohol is consumed. This means individuals no longer receive the same “buzz” from drinking, which over time leads to a reduction in cravings and overall consumption.